1. From Bush Intercontinental Airport, take Will Clayton Boulevard east to U.S. 59 south.
2. From U.S. 59, exit onto Texas 288 and follow it south to the Holcombe Boulevard/Old Spanish Trail exit.
3. Turn right (west) onto Old Spanish Trail.
4. The Proton Therapy Center will be on the left.
5. Proton Therapy will be at 1840 Old Spanish Trail